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CAR T-cell therapy brings sustained, drug-free remission in three autoimmune diseases

CAR T-cell therapy brings sustained, drug-free remission in three autoimmune diseases
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Byjustin cooperShenaz baghaResearch groupUniversity of erlangenNew england journalLupus low disease activity stateActivity indexAmerican collegeEuropean scleroderma trials

Advancing Lupus Care: The Changing Landscape of Treatment

The progression toward more targeted, disease-modifying options for the historically difficult rheumatic disease made more headway in 2023.

United statesAprilm jorgeBrad rovinJack arnoldRosalind ramsey goldmanChris wincupEuropean alliance of associationsOhio state university wexner medical centerDrug administrationKing college hospital lupus unitLeeds centre of rheumaticCollege hospital lupus unitResearch professorNorthwestern university feinberg schoolLeeds centreMassachusetts general hospital

Tapering Lupus Drugs in Stable Patients: Flare Risks Studied

Tapering is best reserved for those in complete remission with stable disease for at least 6 months, although many individual patient characteristics must be taken into account, experts say.

France generalNational university hospitalSingapore generalMerck seronoDafnad gladmanDanielj wallaceLyann nguyenSasha bernatskyNathalie costedoatEli lillyLos angelesBristol myers squibbJiacai choJoant merrillJames mcgillStatistics at paris city university

Galapagos NV: Galapagos announces start of Phase 2 study with selective TYK2 inhibitor, GLPG3667, in patients with active systemic lupus erythematosus

Galapagos NV: Galapagos announces start of Phase 2 study with selective TYK2 inhibitor, GLPG3667, in patients with active systemic lupus erythematosus
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Region flamandeSandra cauwenberghsVan gijselDaniele dambrosioMarieke vermeerschBritish isles lupus assessment groupExchange commissionComposite lupus assessmentCutaneous lupus erythematosus disease areaSeverity index activityLupus low disease activity stateDanieled ambrosioTherapeutic area head immunologyAktien sie

Galapagos announces start of Phase 2 study with selective TYK2 inhibitor, GLPG3667, in patients with active systemic lupus erythematosus

GLPG3667 is an investigational, novel, oral, reversible, and selective tyrosine kinase 2 inhibitor GLPG3667 is currently in development for the treatment of inflammatory and auto-immune diseases.

Region flamandeDaniele dambrosioMarieke vermeerschSandra cauwenberghsVan gijselBritish isles lupus assessment groupExchange commissionComposite lupus assessmentCutaneous lupus erythematosus disease areaSeverity index activityLupus low disease activity stateDanieled ambrosioTherapeutic area head immunology