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Disrupting a core metabolic process in T cells may improve their therapeutic efficacy

Disrupting a core metabolic process in T cells may improve their therapeutic efficacy
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Ludwig lausanne alison jaccardPedro romeroMathias wenesUniversity of lausanneLudwig lausanneAlison jaccard

Disrupting a core metabolic process in T cells may improve their therapeutic efficacy

Disrupting a core metabolic process in T cells may improve their therapeutic efficacy
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Mathias wenesAlison jaccardPedro romeroLudwig lausanne alison jaccardLudwig cancer researchUniversity of lausanneLudwig lausanne

Boosting T Cell Therapy by Disrupting Core Metabolic Process

Boosting T Cell Therapy by Disrupting Core Metabolic Process
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Dinu lipattiLigue genevoisePedro romeroFondation leenaardsHenri dubois ferriLudwig lausanne alison jaccardFondation emma muschampMathias wenesCancer research instituteEuropean molecular biology organizationUniversity of lausanneHelmut horten foundationSwiss cancer researchEuropean research councilEuropean federation of immunological societiesMelanoma research alliance

Disrupting a core metabolic process in T cell

In exploring an aspect of how killer T cells generate the raw materials required for their proliferation, a Ludwig Cancer Research study has uncovered an unexpected link between the immune cells’ metabolism, regulation of gene expression, persistence and functional efficacy that could be exploited using existing drugs to improve cancer immunotherapy.

Mathias wenesFondation emma muschampPedro romeroLigue genevoiseHenri dubois ferriFondation leenaardsLudwig lausanne alison jaccardDinu lipattiEuropean federation of immunological societiesSwiss national science foundationSwiss cancer researchEuropean molecular biology organizationHelmut horten foundationMelanoma research allianceCancer research instituteEuropean research council