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CRISPR gene-editing therapies need more diverse DNA to realize their full potential

The genetic data that underpins CRISPR has a big diversity problem.

United statesSean misekJonathan wiggsSarah tishkoffTammy ljungbladLuca pinelloDaniel bauerEuropean commissionAmerican society of human geneticsNational human genome research instituteMedicaid servicesUniversity of pennsylvaniaHealth disparitiesHuman genetics genomics workforce surveyDrug administrationNational institutes of health

With the promise of saving millions of lives, CRISPR medicine is born

The approval of the first DNA editing therapy opens the door to a revolution in the treatment of a multitude of diseases, such as cancer

Santa polaUnited statesUnited kingdomComunidad autonoma de catalunaDavid liuFrancis mojicaStuart orkinFeng zhangEmmanuelle charpentierDavid altshulerJennifer doudnaSekar kathiresanSyriol jonesLuca pinelloAssociation for responsible researchVertex pharmaceuticals

Using gene editing to fight deadly genetic diseases

Gene editing holds enormous promise for tackling devastating diseases, according to experts who spoke at Harvard Chan School's PQG conference.

United statesDavid liuDavid liu sekar kathiresanXihong linLuca pinelloSekar kathiresan beverly davidsonBeverly davidsonSekar kathiresanBroad instituteHarvard chan schoolMerkin institute of transformative technologies in healthcareProgram in quantitative genomicsUniversity of pennsylvania children hospital philadelphiaHarvard medical schoolPerelman school of medicineQuantitative genomics

CRISPR s ancestry problem misses cancer targets in those of African descent | Science

CRISPR s ancestry problem misses cancer targets in those of African descent | Science
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New yorkUnited statesDana farber cancer instituteMassachusetts institute of technologyHarvard universityRameen beroukhimAdam phillippyOlorunseun ogunwobiMelissa davisSean misekLuca pinelloJesse boehmBroad instituteNational human genome research instituteMassachusetts general hospitalCancer dependency map

Stability AI backs effort to bring machine learning to biomed

Stability AI, the company behind Stable Diffusion, is backing a community effort to apply AI techniques to biomedicine.

Soult ukpyolsiSouth koreaUnited statesDeepmind alphafoldMinkyung baekDevin coldeweyEmad mostaqueSalesforce progenLuca pinelloUniversity college londonHospital harvard medical schoolSeoul national universityUniversity of parmaStable diffusionMassachusetts general hospitalHarvard medical school