Colon Intestine-Chip Introduced for Research on Inflammatory Intestinal Diseases
March 17, 2021
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Emulate launched the Colon Intestine-Chip for researchers investigating inflammatory intestinal diseases. The complete, lab-ready Human Emulation System and the Colon Intestine-Chip will allow researchers to recapitulate specific human colon cell functionality, gain a greater understanding of mechanisms of inflammation, and investigate potential drug targets, says Lorna Ewart, executive vice president of science, at Emulate, adding that the model will also accelerate identification of drug candidates to prevent inflammatory damage that are more likely to translate to the clinic.
The company plans to continue developing further applications for the Colon Intestine-Chip, enabling researchers to study immune cell recruitment and how the gut microbiome affects the epithelial barrier.
Published: Dec 21, 2020
BOSTON, Dec. 21, 2020 /PRNewswire/ Emulate, Inc., a leading provider of advanced
in vitro models, today unveiled the Emulate Brain-Chip, which is designed for neuroscience researchers investigating neuroinflammatory disease and for drug developers seeking to improve drug discovery for neurodegenerative diseases such as Alzheimer s and Parkinson s. The comprehensive model incorporates cells from the human brain, including the blood-brain barrier, in a dynamic microenvironment which enables cell-cell interaction.
Emulate Organ-Chips, including the Brain-Chip, are designed to enable researchers to investigate the safety and efficacy of therapeutic treatments in development, in order to reduce the high drug development failure rates that result from a poor understanding of drug mechanism of action, toxicity, pharmacokinetic profile, or overall applicability and translation of animal and