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BLINCYTO® Demonstrated Significantly Prolonged Event-Free Survival Compared With Consolidation Chemotherapy In Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia

Amgen today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia were published in The Journal of the American Medical Association . 1 BLINCYTO … Amgen (NASDAQ:AMGN) today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® (blinatumomab) compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL) were published in The Journal of the American Medical Association (JAMA) . 1

BLINCYTO® (Blinatumomab) Demonstrated Significantly Prolonged Event-Free Survival Compared With Consolidation Chemotherapy In Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia

Share this article Share this article THOUSAND OAKS, Calif., March 2, 2021 /PRNewswire/ Amgen (NASDAQ:AMGN) today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® (blinatumomab) compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL) were published in The Journal of the American Medical Association (JAMA). 1 BLINCYTO demonstrated significantly prolonged event-free survival (events were defined by relapse, death, second malignancy, or failure to achieve complete remission) compared with chemotherapy. After a median of 22.4 months follow-up, 69% of patients treated with BLINCYTO were alive and event-free compared with 43% of patients treated with chemotherapy. Additionally, following treatment with BLINCYTO, 93% of patients with MRD at baseli

CNN CNN Special Report October 13, 2019 01:17:00

already on. some think this honeymoon period that kids like vivian experienced might be explained by her liver. cbd works in the liver, in the enzymes that break down the other prescription medicines. and cbd inhibits those enzymes so that they don t break down pharmaceuticals to the extent that they should be broken down, allowing them to get a higher level. and perhaps more effective or perhaps more toxic. the fact that cbd can affect your liver enzymes and change the way drugs interact with your body could potentially be very dangerous. 60% of medications are broken down in the liver that could be anktded by cbd use. they include drugs you might use every day, antibiotics, anti-histamines, antidepressants. it s not entirely benign. and that s one of my concerns about the widespread use of cbd.

CNN Weed 5 The CBD Craze September 30, 2019 00:17:00

there is a suspicion that maybe it works by increasing the blood level of the anti-seizure medicine that the children were already on. some think this honeymoon period that kids like vivian experienced might be explained by her liver. good job. cbd works in the liver in the enzymes that break down other prescription medicines and cbd inhibits those enzymes so that they don t break down pharmaceuticals to the extent that they should be broken down allowing them to get a higher level and perhaps more effective or perhaps more toxic. the fact that cbd can affect your liver enzymes and change the way drugs interact with your body could potentially be very dangerous. 60% of medications are broken down in the liver by a group of enzymes that could be affected by cbd use. they include drugs you might use every day, antibiotics,

CNN Weed 5 The CBD Craze September 30, 2019 03:17:00

maybe it works by increasing the blood level of the anti seizure medicine that the children were already on. some think this money moon period kids like vivian experienced might be explained by her liver. good job. cbd works in the liver, in the enzymes that break down other prescription medicines and cbd inhibits those enzymes so that they don t break down pharmaceuticals to the extent that they should be broken down allowing them to get a higher level and perhaps more effective or perhaps more toxic. the fact that cbd can affect your liver enzymes and change the way they interact with your body could be dangerous. 60% are broken down in the liver that could be affected by cbd use like drugs you might use every day.

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