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Children and young adults with Down Syndrome four times more likely to have diabetes

Children and young adults with Down Syndrome four times more likely to have diabetes
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United kingdomCity ofAndre strydomLif chanMartinc gullifordAishaa aslamR asaad bakshAli chanSarahe papeUnited kingdom clinical practice research datalinkDiabetes careDown syndromeBody mass indexMolecular endocrinologyConsultant paediatric endocrinologistQueen mary university

- Queen Mary University of London

- Queen Mary University of London
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Weizmann Institute Uncovers Secret of Hunger Switch in the Brain | The Jewish Press - JewishPress com | Jewish Press News Desk | 4 Iyyar 5781 – April 16, 2021

Photo Credit: Image by Gerd Altmann from Pixabay Being constantly hungry, no matter how much you eat â that’s the daily struggle of people with genetic defects in the brain’s appetite controls, and it often ends in severe obesity. In a study published in Science on April 15, researchers at the Weizmann Institute of Science, together with colleagues from the Queen Mary University of London and the Hebrew University of Jerusalem, have revealed the mechanism of action of the master switch for hunger in the brain: the melanocortin receptor 4, or MC4 receptor for short. They have also clarified how this switch is activated by setmelanotide (Imcivree), a drug recently approved for the treatment of severe obesity caused by certain genetic changes. These findings shed new light on the way hunger is regulated and may help develop improved anti-obesity medications.

Israel generalMoran shalev benamiOksana degtjarikVadivel prabaharGerd altmannYoav pelegFabrizio fierroNicolasj rothVidicha chunilalPeterj mccormickLif chanDanny ben zviAmandeep kaur gillJoaquin bottaWeizmann institute of scienceTauro career development

The Hunger Games: Uncovering the Secret of the Hunger Switch in the Brain - Chemistry | Weizmann Wonder Wander

Being constantly hungry, no matter how much you eat, is a daily struggle for people with genetic defects in the brain s appetite controls, and it often ends in severe obesity. In a study published in Science on April 15, researchers at the Weizmann Institute of Science, together with colleagues from the Queen Mary University of London and the Hebrew University of Jerusalem, have revealed the mechanism of action of the master switch for hunger in the brain: the melanocortin receptor 4, or MC4 receptor for short. They have also clarified how this switch is activated by setmelanotide (Imcivree), a drug recently approved for the treatment of severe obesity caused by certain genetic changes. These findings shed new light on the way hunger is regulated and may help develop improved anti-obesity medications.

Israel generalMoran shalev benamiOksana degtjarikVadivel prabaharFabrizio fierroYoav pelegNicolasj rothVidicha chunilalPeterj mccormickLif chanDanny ben zviAmandeep kaur gillJoaquin bottaWeizmann life sciences core facilities departmentQueen mary university of londonHebrew university of jerusalem

The Hunger Games: Uncovering the secret of the hunger switch in the brain

E-Mail Being constantly hungry, no matter how much you eat - that s the daily struggle of people with genetic defects in the brain s appetite controls, and it often ends in severe obesity. In a study published in Science on April 15, researchers at the Weizmann Institute of Science, together with colleagues from the Queen Mary University of London and the Hebrew University of Jerusalem, have revealed the mechanism of action of the master switch for hunger in the brain: the melanocortin receptor 4, or MC4 receptor for short. They have also clarified how this switch is activated by setmelanotide (Imcivree), a drug recently approved for the treatment of severe obesity caused by certain genetic changes. These findings shed new light on the way hunger is regulated and may help develop improved anti-obesity medications.

Israel generalMoran shalev benamiOksana degtjarikVadivel prabaharFabrizio fierroYoav pelegNicolasj rothVidicha chunilalPeterj mccormickLif chanDanny ben zviAmandeep kaur gillJoaquin bottaWeizmann institute of scienceTauro career developmentLeadership program