Nationalism has long been overlooked by scholars who study international relations or civil wars.This talk highlights the crucial role of nationalism - the demand that states be ruled by representatives of the nation - in the political transformations of the world during the past 250 years and the wars between and within states that have accompanied this process. The talk also
GPCR-targeting drugs make up around a third of those approved by the FDA, yet often come with side effects. New research into the mechanisms of GPCR activation could help design drugs to prevent side effects.
Scientists Illuminate Mechanism of Common Drug Target miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
New imaging technique captures movies of receptors on the surface of living cells
A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children s Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.
The researchers used the technique to zoom in on individual receptor proteins on the surface of living cells to determine if the receptors work solo or come together to work as pairs. This work appeared in the April issue of
Nature Methods.
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NEW YORK, NY A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children s Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.
The researchers used the technique to zoom in on individual receptor proteins on the surface of living cells to determine if the receptors work solo or come together to work as pairs. This work appeared in the April issue of
Nature Methods. If two different receptors come together to form a dimer with distinctive function and pharmacology, this might allow for a new generation of drugs with greater specificity and reduced side effects, says Jonathan Javitch, MD, PhD, the Lieber Professor of Experimental Therapeutics in Psychiatry at VP&S.