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Researchers Find Shared Multiomic Molecular Dysregulations in Brains With PTSD and MDD

The investigators are optimistic that the data can establish stress-related pathways while revealing potential therapeutic options for patients with major depressive disorder and post-traumatic stress disorder.

Joel kleinmanCharlesb nemeroffKerry resslerNikolaosp daskalakisTranslational bioinformatics laboratory at mclean hospitalNeurobiology of fear laboratory at mclean hospitalHarvard medical schoolDepartment of psychiatryBehavioral sciences at dell medical schoolLieber institute brain repositoryLieber institute for brain developmentClinical sciencesDivision of depressionTranslational bioinformatics laboratoryMclean hospitalAnxiety disorders

Researchers unveil shared and unique brain molecular dysregulations in PTSD and depression

Researchers analyzed multi-omic data from 231 people with PTSD or depression to uncover distinct molecular differences that might affect systems such as the nervous and immune systems, to contribute to these mental health conditions.

Joel kleinmanNikolaosp daskalakisKerry resslerCharlesb nemeroffLieber institute brain repositoryNeurobiology of fear laboratory at mclean hospitalDepartment of psychiatryTranslational bioinformatics laboratory at mclean hospitalBehavioral sciences at dell medical schoolDivision of depressionClinical sciencesHarvard medical schoolLieber institute for brain developmentTranslational bioinformatics laboratoryMclean hospitalHarvard medical

Molecular Signatures of PTSD and MDD

Molecular Signatures of PTSD and MDD
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United statesKerry resslerCharlesb nemeroffJoel kleinmanNikolaosp daskalakisLieber institute brain repositoryUniversity of texas at austinTranslational bioinformatics laboratory at mclean hospitalLieber institute for brain developmentDepartment of psychiatryDivision of depressionBehavioral sciences at dell medical schoolHarvard medical schoolNeurobiology of fear laboratory at mclean hospitalClinical sciencesMclean hospital

Pioneering new study uncovers insights into P

Pioneering new study uncovers insights into P
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United statesCharlesb nemeroffKerry resslerJoel kleinmanNeurobiology of fear laboratory at mclean hospitalDell medical schoolDepartment of psychiatryDivision of depressionLieber institute for brain developmentLieber institute brain repositoryNational institute of mental healthUniversity of texas at austinHarvard medical schoolBehavioral sciences at dellBehavioral sciencesMclean hospital

Researchers unveil shared and unique brain mo

Researchers unveil shared and unique brain mo
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United statesJoel kleinmanAdamx maihoferBenjaminb sunBertrandr huberNikolaosp daskalakisChristopherp dipietroRahula bharadwajLeonardo collado torresKerryj resslerEricb dammerDeanna rossChia yen chenChris chatzinakosJustinaf lugenbNick eagles