Much wisdom we would have missed out on. The one and only president for sure trevor of the Carnegie Corporation. Ishmael the director of the library in alexandria, and they are joining us to celebrate your service. We are also lucky to be joined by the latvian ambassadors to the United States committee acting librarian of Congress David howell and Jane Mcauliffe the director of outreach and delegates to the board. Grace mckenna and come i havent seen her come there she is, whose family has done so much to shape this Institution Come and Diana Davis Spencer who has been a great friend to our work. The gatherings like this remind me what a impact the center has around the globe including hundreds in russia and ukraine and even now we pick the best scholars and the most brilliant staff to work on the most important issues and we learned that from you. You always scholarship at the heart of the work. No one who knows you would be surprised. Some may already know this but jim and his daught
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Abstract
A new way to alter the genome of bacteriophages helps produce large libraries of variants, allowing these bacteria-killing viruses to be designed to target species harmful to human health.
Main text
Antibiotics are usually quite effective at killing bacteria that cause disease, but they often end up eliminating huge swaths of microorganisms beneficial to health . Limiting this collateral damage by solely targeting pathogenic bacteria remains challenging, as only slight differences separate harmful and beneficial bacterial species.
An alternative treatment to chemical antibiotics could be to harness viruses called bacteriophages (or phages), which have evolved to recognize and prey on highly specific strains of bacteria (Abedon et al., 2011). Yet engineering phages to target harmful bacterial species requires scalable genetic tools that can precisely alter the genomes of these viruses. Now, in eLife, Srivatsan Raman and colleagues at University of Wisconsin-Madison –