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Aptevo Therapeutics Announces Expansion Phase of Lead Anti-Leukemia Drug APVO436 in Adult Patients with Acute Myeloid Leukemia

(0) Initiates Multi-Center, Multi-Arm Trial Using Active Dose Identified in the Dose Escalation Phase of the Trial SEATTLE, WA / ACCESSWIRE / May 27, 2021 / Aptevo Therapeutics Inc. ( Aptevo ) (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immuno-oncology therapeutics based on its proprietary ADAPTIR TM and ADAPTIR-FLEX TM platform technologies today announced that the company has initiated the expansion phase of lead anti-leukemia drug candidate, APVO436, in adult patients with acute myeloid leukemia (AML) with a multi-center, multi-arm trial using the active recommended dose identified in the dose escalation phase (Part 1) of the study. During Part 1, APVO436 exhibited a manageable side effect profile, encouraging single agent activity and a promising benefit to risk profile in relapsed AML patients. The Company has plans to submit data from the dose escalation phase for publication later this year.

Aptevo Therapeutics Reports Positive Phase 1 Clinical Data for Its Lead Leukemia Drug Candidate APVO436 in Adults With Relapsed Acute Myeloid Leukemia

A giant of modern medicine : Dr Emil Freireich gave young leukemia patients hope with his groundbreaking research He died at 93

‘A giant of modern medicine’: Dr. Emil Freireich gave young leukemia patients hope with his groundbreaking research. He died at 93. Adrianna Rodriguez, USA TODAY © MD Anderson Cancer Center Emil J Freireich MD, designs continuous-flow blood separators to divide donor blood into cellular components to obtain white blood cells or platelets; the technique will later be adapted for both immunotherapy and bone marrow transplantation. 1958 Dr. Emil J. Freireich, a legendary cancer doctor whose groundbreaking research gave hope to generations of children diagnosed with leukemia, died Feb. 1. He was 93. He passed away peacefully at the University of Texas MD Anderson Cancer Center in Houston, where he worked for 50 years, from 1965 to 2015.

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