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 E-Mail Targeted neuromodulation tailored to individual patients distinctive symptoms is an increasingly common way of correcting misfiring brain circuits in people with epilepsy or Parkinson s disease. Now, scientists at UC San Francisco s Dolby Family Center for Mood Disorders have demonstrated a novel personalized neuromodulation approach that at least in one patient was able to provide relief from symptoms of severe treatment-resistant depression within minutes. The approach is being developed specifically as a potential treatment for the significant fraction of people with debilitating depression who do not respond to existing therapies and are at high risk of suicide. The brain, like the heart, is an electrical organ, and there is a growing acceptance in the field that the faulty brain networks that cause depression just like epilepsy or Parkinson s disease could be shifted into a healthier state by targeted stimulation, said Katherine Scangos, MD, PhD, an assist

San franciscoUnited statesEdward changLeo sugrueKatherine scangosAndrew krystalGhassan makhoulSanfordi weillUniversity of californiaDagmar dolby family fundDepartment of neurological surgeryUs national institutes of healthEpilepsy centerDepartment of psychiatryHelen diller medical center at parnassus heightsDolby center