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Antibiotics remain the primary treatment for many bacterial infections, including those that negatively impact our oral health. In the USA, it has been estimated that dentists prescribe approximately 10% of outpatient antibiotics. Yet the spread of antibiotic resistance due to inappropriate prescribing and overuse presents a major global health risk. Antibiotic resistance challenges the effective delivery of a number of the United Nations Sustainable Development Goals, including SDGs 1, 2, 3, 8 and 10.