Announcing HAProxy 2.4
HAProxy 2.4 adds exciting features such as support for HTTP/2 WebSockets, authorization and routing of MQTT and FIX (Financial Information Exchange) protocol messages, DNS resolution over TCP, server timeouts that you can change on the fly, dynamic SSL certificate storage for client certificates sent to backend servers, and an improved cache; it adds a built-in OpenTracing integration, new Prometheus metrics, and circuit breaking improvements.
This release was truly a community effort and could not have been made possible without all of the hard work from everyone involved in active discussions on the mailing list and the HAProxy project GitHub. The HAProxy community provides code submissions covering new functionality and bug fixes, documentation improvements, quality assurance testing, continuous integration environments, bug reports, and much more. Everyone has done their part to make this release possible! If you’d like to join this amazing community, y
Ein Strategiespiel wie Songs of Conquest gab es schon viel zu lange nicht mehr
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Economic Bulletin
Summary
While the recovery in global demand and the sizeable fiscal stimulus are supporting global and euro area activity, the near-term economic outlook remains clouded by uncertainty about the resurgence of the pandemic and the roll-out of vaccination campaigns. Persistently high rates of coronavirus (COVID-19) infection and the associated extension and tightening of containment measures continue to constrain economic activity in the short term. Looking ahead, progress with vaccination campaigns and the envisaged gradual relaxation of containment measures reinforce the expectation of a firm rebound in economic activity in the course of 2021. Inflation has picked up over recent months on account of some idiosyncratic and temporary factors and an increase in energy price inflation. At the same time, underlying price pressures remain subdued in the context of significant economic slack and still weak demand.
Main findings from the ECB’s recent contacts with non-financial companies
Prepared by Gwenaël Le Breton, Richard Morris and Moreno Roma
This box summarises the results of contacts between ECB staff and representatives of 66 leading non-financial companies operating in the euro area. The exchanges took place between 23 March and 1 April 2021.
Contacts reported increasing constraints and restrictions on their ability to respond to strong or growing actual or latent demand. Stricter and more prolonged coronavirus (COVID-19) containment measures continued to severely restrict activity in services dependent on social contact. Moreover, many contacts in the manufacturing sector emphasised supply constraints. As a result, many firms’ activity was stable or contracting despite strong growth in order books or indications of substantial latent demand. Overall, activity in the first quarter was seen to have contracted in most parts of the retail, consumer services and energy sectors, a
Decentralized Clinical Trials: Surviving & Thriving in the Clinical Research World of COVID-19
by Zach Henderson, Chief Commercial Officer, Glooko
Zach Henderson, Chief Commercial Officer, Glooko
As with so many aspects of our daily lives, the impact of the COVID-19 pandemic on clinical trials was both widespread and monumental. Thousands of trials an estimated 80% of non-COVID-19 trials came to a halt or were interrupted by the pandemic, which challenged the ability to conduct trials safely and effectively and was complicated by the reality that trials often deal with the populations most at risk from COVID-19 exposure
1.
In response, clinical researchers turned to a range of solutions to address the effects of the pandemic on trials. And while, in most cases, it’s premature to definitively determine which solutions will outlast the pandemic, probably the most widely used and enduring will be the decentralized model for conducting clinical trials, including the digital health
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