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P-glycoprotein shows ability to remove a toxin associated with Alzheimer s from the brain \A team of SMU biological scientists has confirmed that P-glycoprotein (P-gp) has the ability to remove a toxin from the brain that is associated with Alzheimer s disease. The finding could lead to new treatments for the disease that affects nearly 6 million Americans. It was that hope that motivated lead researchers James W. McCormick and Lauren Ammerman to pursue the research as SMU graduate students after they both lost a grandmother to the disease while at SMU. In the Alzheimer s brain, abnormal levels of amyloid-β proteins clump together to form plaques that collect between neurons and can disrupt cell function. This is believed to be one of the key factors that triggers memory loss, confusion and other common symptoms from Alzheimer s disease.

New yorkUnited statesJohn wiseJamesw mccormickLauren ammermanMike chenPia vogelEmily hendersonDepartment of biological sciencesSouthern methodist universityBiological sciencesDrug discoveryபுதியது யார்க்ஒன்றுபட்டது மாநிலங்களில்ஜான் பாண்டித்தியம்மைக் சென்