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<p>Scientists have unexpectedly discovered that the weakened form of the bacteria <em>Coxiella burnetii</em> (<em>C. burnetii</em>) not typically known to cause disease, naturally acquired an ability to do so. <em>C. burnetii</em> causes Q Fever in humans and its weakened forms are those used for scientific purposes. Subsequently, the scientists identified the genetic mutation responsible for the increased ability to cause disease (virulence) and created a form of the bacteria without the genetic flaw that could safely be used for research. The study, by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health and collaborators at Washington State University and Northern Arizona University, is published in <em>Nature Communications</em>.</p>

United statesNational institute of allergyUs centers for diseaseUs department of healthNorthern arizona universityNational institutes of healthWashington state universityLaboratory of bacteriologyResearch scholarHuman servicesNature communicationsNational instituteInfectious diseasesNational institutesDisease controlBiosafety level