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Maintenance antipsychotic trials and the effect of withdrawal – Authors reply

We thank Klaus Munkholm and colleagues for their valuable Correspondence. First, we would like to mention that this Correspondence does not call into question the main results of our network meta-analysis1 about differences between antipsychotics, for which placebo primarily served as a reference intervention and for which sensitivity and meta-regression analyses on tapering did not yield different results.

Geodon richterKlaus munkholmBoehringer ingelheimElsevier ltdGerman ministry of educationBull openGerman ministry

Official Guidelines on Antidepressant Discontinuation Fail Practitioners and Patients

A review of clinical practice guidelines for antidepressant discontinuation from across the English-speaking world reveals major pitfalls.

United statesNew zealandUnited kingdomKarsten juhlKlaus munkholmTherapeutic advancesClinical practice guidelinesClinical practice guidelines

Researchers Set the Record Straight on Controversial Zoloft Study

An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

New zealandGlyn lewisMichaelp hengartnerGemma lewisKlaus munkholmZurich university of applied sciencesNordic cochrane centerUniversity of aucklandLancet psychiatryZurich universityApplied sciencesAsger sand paludan mNordic cochraneBruce arrollDepression treatmentLancet psychiatry

Positive Antidepressant Study Misleading and Erroneous

An analysis of last year’s positive finding in The Lancet about antidepressant efficacy shows errors, obfuscations, and misrepresentations.

United kingdomKlaus munkholmAndrea ciprianiBritish medical associationNordic cochrane centerCochrane collaborationNordic cochraneCochrane handbookHamilton depression rating scalePlacebo effect

Antidepressant Effects on Serotonin Plateau at the Minimum Recommended Dose

Antidepressant Effects on Serotonin Plateau at the Minimum Recommended Dose
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Klaus munkholmHenricusg ruhNordic cochrane centerMolecular psychiatry

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