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Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes worldwide. The number affected is increasing rapidly with alarming trends in children and young adults (up to age 40 years). Early detection and proactive management are crucial for prevention and mitigation of microvascular and macrovascular complications and mortality burden. Access to novel therapies improves person-centred outcomes beyond glycaemic control. Precision medicine, including multiomics and pharmacogenomics, hold promise to enhance understanding of disease heterogeneity, leading to targeted therapies.

United kingdomUnited statesCity ofMosalman haghighiFiatarone singhCardiovasc diabetolEndocrinol lausanneVan rhoonJ clin endocrinolGurushantappa mangshettyClin nutrPharmaceuticals baselDiabetes prevention program outcomes studyAmerican college of sports medicineJ phys act healthAmerican diabetes association