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Half of Negative Clinical Trial Results on Antidepressants Were Not Published or Were Spun as Positive, Researchers Find

Even the FDA does not always get all relevant clinical trials before approving drugs, according to published reports.

United statesUnited kingdomKim boesenErickh turnerMichaelp hengartnerKamran abbasiThomas szaszScience universityCongressional black caucus foundation annual legislativeNordic cochrane centreDrug administrationOregon healthZurich university of applied sciencesOregon health science universityCitizens commission on human rightsNational affairs office

Did Pharma Companies Hide Failed ADHD Drug Studies From Regulators?

Researchers find more than half of drug trials missing from pharma applications to approve ADHD medication.

United kingdomKim boesenMedizinprodukte bfarNordic cochrane centreDrug administrationAustralian therapeutic goods administrationEuropean unionJanssen pharmaceuticalsInternational council for harmonisationEuropean medicines agencyTeam leaderHealth canadaClinical epidemiologyGerman bundesinstitutDivision directorInternational council

Medical journal requirements for clinical trial data sharing: Ripe for improvement

Florian Naudet and co-authors discuss strengthening requirements for sharing clinical trial data.

United statesUnited kingdomUppsala lanKim boesenAngela swaine verdierUppsala universityYale universityUnited states national institutes of healthInternational committee of medical journal editorsNational institutes of healthJohn arnold foundationReproducibility in therapeutic researchSwedish society of medicineBlanceflor foundationCollaboration for research integrityYale university open data access

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