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A small molecule could provide a new therapeutic approach against organ fibrosis. Using genome-wide association (GWA) assays, a group of researchers of the Westmead Institute for Medical Research in Sydney identified Mer tyrosine kinase (MERTK) as a candidate to study fibrosis and showed that its inhibition with the experimental compound reduced this condition in mouse models’ liver, kidneys and lungs.

New south walesMohammed eslamWestmead institute for medical researchWestmead instituteMedical researchBioworld scienceEndocrine metabolicIdiopathic pulmonary fibrosisLiver fibrosisKidney fibrosisUnc 569