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il 19, 2021) – A new study from University of Kentucky Markey Cancer researchers shows that Artemisia annua, a plant that has been traditionally used for its anti-malaria components, shows promise in treating ovarian cancer.    The study, recently published in Diagnostics, demonstrates artesunate, synthesized from Artemisia annua, kills ovarian cancer cells in multiple preclinical model systems.  Despite accounting for only 1.3% of all new cancer cases, 2.3% of cancer deaths in 2021 are predicted to be caused by ovarian cancer. The current standard of care for advanced ovarian cancer, which hasn’t changed since 2003, is the use of two chemotherapy agents: carboplatin and paclitaxel. In this study, the researchers determined that artesunate, both alone and in combination with carboplatin and paclitaxel, has anticancer activity at concentrations that are achievable in the clinic, which support the further clinical development of this strategy.   

United statesUnited kingdomJill kolesarUniversity of kentucky markey cancerUnited kingdom college of pharmacyCollege of agricultureCollege of pharmacyKentucky markey cancerUnited kingdom collegePrecision medicineSpindletop farmஒன்றுபட்டது மாநிலங்களில்ஒன்றுபட்டது கிஂக்டம்ஜில் க்கோளெசார்பல்கலைக்கழகம் ஆஃப் கெந்‌டகீ மார்‌க் புற்றுநோய்ஒன்றுபட்டது கிஂக்டம் கல்லூரி ஆஃப் மருந்தகம்