Mcdonalds, apparently called police and ambulance. And they were taken to stanford hospital where theyre being treated. The good news, of course, is that these are not life threatening injuries. The bad news, a mother and child shot, and the motive we just dont know. There has also been a Fatal Shooting in east palo alto, just a few blocks from where the menlo park victims were found. Paramedics were called to a man shot in the head at capital avenue and bell street around 9 this evening. The victim was pronounced dead at the scene. Well, dozens of people walked along San Franciscos waterfront today to show support for gun control. The event was organized by the Group One Million Moms for gun control. It was intended to show solidarity for these events across the country, the largest of which were held in washington, d. C. Members of the newtown, connecticut, community joined in with thousands demanding action. If it can happen in newtown, it can happen in any town, in any city, in any
Emulating a target trial reduces the potential for bias in observational comparative effectiveness research. Owing to feasibility constraints, large cohort studies often use electronic health records without validating key variables or collecting additional data. A case-control design allows researchers to validate, supplement, or collect additional data on key measurements in a much smaller sample compared with the entire cohort. In this article, Rasouli and colleagues describe methods to emulate a target trial using a nested case-control design, and provide a detailed guideline, an analytical program, and results of a clinical example.
#### Summary points
Randomized controlled trials are considered the ideal study design for comparative effectiveness research. Given that such trials are usually costly, lengthy, and, in some instances, unethical or infeasible, interest is increasing in using observational studies such as those conducted using data from electronic health records and
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