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Fixed-Dose Combination Pill Outperforms Monotherapy for Pulmonary Hypertension

Fixed-dose combination therapy provides better results than monotherapy for pulmonary hypertension

Patients with pulmonary arterial hypertension (high blood pressure in the arteries that supply the lungs, also called PAH) had approximately double the reduction in pulmonary vascular resistance (PVR) if they took the PAH medications macitentan (10 mg) and tadalafil (40 mg) together in a single tablet rather than either drug alone, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

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