Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.
<p>The structure and functions of the tip of migrating neurons remain elusive. Here, a research group led by Kazunobu Sawamoto, Professor at Nagoya City University and National Institute for Physiological Sciences, and by Chikako Nakajima and Masato Sawada, staff scientists in his laboratory, has elucidated that the PTPσ-expressing growth cone senses the extracellular matrix and drives neuronal migration in the injured brain, leading to functional recovery.</p>
Discovery of Growth Cone Boosts Brain Injury Recovery miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
In the mammalian brain, neural stem cells exist even after birth, and new neurons are produced. As these new neurons mature, they form synapses with existing neurons to create functional neural circuits. For the brain to develop and function normally, it is important to maintain an appropriate number of synapses, but the mechanism to regulate the number of synapses has not been fully understood.