An international research collaboration led by the University of Tsukuba have used Raman microspectroscopy and Raman imaging to detect changes in the elastic and collagen fibers in the aortic wall characteristic of ascending thoracic aortic aneurysms (aTAAs). This has the potential to be used as a low-risk, early diagnostic tool to detect pre-aneurysmal lesions before serious complications develop.
Nationwide network to improve animal welfare and research is launchedAnimal experiments contribute to a better understanding of diseases in medicine and help in the development of many new diagnostic procedures and therapies. Despite the development
Trophoblast motility in a gelatin hydrogel
New Rochelle, NY, December 18, 2020 Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized hydrogel is described in the peer-reviewed journal
Tissue Engineering, Part A. Click here to read the full-text article free on the
Tissue Engineering website through January 18, 2020.
This valuable new tool, based on a methacrylamide-functionalized gelatin hydrogel, can be used for three-dimensional trophoblast spheroid motility assays. It can resolve quantifiable differences in outgrowth area and viability in the presence of a known invasion promoter and a known invasion inhibitor.