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Breaking Down the Science of the Blood-Brain Barrier

Breaking Down the Science of the Blood-Brain Barrier
tmcnet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from tmcnet.com Daily Mail and Mail on Sunday newspapers.

White houseDistrict of columbiaUnited statesStanford universitySan franciscoSouth koreaMission bayKaterina akassoglouTony wyssJulie langelierLos angelesAndrew yangLennart muckeAndrewc yangMassachusetts institute of technologyDepartment of anatomy

Blood-clotting protein fibrin triggers MS brain inflammation: Study | Multiple Sclerosis News Today

Blood-clotting protein fibrin triggers MS brain inflammation: Study | Multiple Sclerosis News Today
multiplesclerosisnewstoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from multiplesclerosisnewstoday.com Daily Mail and Mail on Sunday newspapers.

Lennart muckeKaterina akassoglouAndrew mendiolaUniversity of california san franciscoGladstone institute of neurological diseaseNeurovascular brain immunologyGladstone institutesCalifornia sanGladstone institute

How Blood That Leaks into the Brain Makes Immune Cells Toxic

Exposure to blood leaking into the brain turns on harmful genes in microglia, transforming them into toxic cells that can destroy neurons.

Alex picoLennart muckeNevan kroganAndrew mendiolaKaterina akassoglouQuantitative biosciences instituteGladstone institute of neurological diseaseGladstone institutesNature immunologyNeurovascular brain immunologyBioinformatics coreGladstone institute

Study shows how blood makes the brain s immune cells toxic

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive dysfunction and motor impairment.

Nevan kroganAlex picoKaterina akassoglouLennart muckeAndrew mendiolaDanielle ellisGladstone institute of neurological diseaseQuantitative biosciences instituteGladstone institutesSenior investigatorNature immunologyNeurovascular brain immunologyBioinformatics coreGladstone institute

Revealing how blood triggers brain disease

Researchers at Gladstone Institutes led by Senior Investigator Katerina Akassoglou, PhD, showed that exposure to blood leaking into the brain turns on harmful genes in microglia, transforming them into toxic cells that can destroy neurons.

San franciscoUnited statesMission bayJeffrey johnsonEilidh macdonaldZhaoqi yanPilars alzamoraMehdi bouhaddouGyoung shinGayathri muthukumarScott zamvilAayushi agrawalLennart muckeKaterina akassoglouClairice pearceAlex pico