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tRNA fragments are involved in poststroke immune reactions

 E-Mail Sebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinformatic methods. Recently, small RNAs have become more and more interesting for researchers, primarily because of their extensive regulatory functions. To examine these functions in stroke, Lobentanzer joined Katarzyna Winek of Hebrew University, Jerusalem, to study microRNAs and tRNA fragments in blood samples from ischemic stroke patients collected at Charité, Berlin. tRNA fragments, which until now were only thought to be debris of the amino acid-transporting tRNAs, have recently been shown to possess biological functions; naturally, we were very interested in that, explains the pharmacologist.

Monocytic tRNA fragments play key role in poststroke immune reactions

Sebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinformatic methods. Recently, small RNAs have become more and more interesting for researchers, primarily because of their extensive regulatory functions.

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