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Connections by Karl Deisseroth review – artful insights into the brain

Connections by Karl Deisseroth review – artful insights into the brain
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Neuroscientist Karl Deisseroth: Coronavirus has changed us all | Science and nature books

The neuroscientist and psychiatrist explains Zoom fatigue - and why the conditions of the pandemic can induce an ‘altered state’<br>

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Milestone : Scientists partially restore blind man s vision with gene therapy

Last Updated: Milestone : Scientists Partially Restore Blind Man s Vision With ’gene Therapy’ “It’s a big step for the field, neurobiologist Flannery said. Most important thing is that it is safe and permanent, he added about blind man s vision. IMAGE: NATURE JOURNAL In a first, scientists in Europe and the US have been able to partially restore the eyesight for a blind man who suffered photoreceptor disease nearly 40 years ago. Employing the technique known as optogenetics, which involves altering cells such that they manufacture the light-sensitive proteins, scientists were able to get the vision back for the 58-year old patient. Now, he can recognize people, do the counting, locate and touch different objects.

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Injection of Light-Sensitive Proteins Restores Blind Man s Vision

Advertisement After 40 years of blindness, a 58-year-old man can once again see images and moving objects, thanks to an injection of light-sensitive proteins into his retina. The study, published on 24 May in Nature Medicine, is the first successful clinical application of a technique called optogenetics, which uses flashes of light to control gene expression and neuron firing. The technique is widely used in laboratories to probe neural circuitry and is being investigated as a potential treatment for pain, blindness and brain disorders. The clinical trial, run by the company GenSight Biologics, headquartered in Paris, enrolls people with retinitis pigmentosa (RP): a degenerative disease that kills off the eye’s photoreceptor cells, which are the first step in the visual pathway. In a healthy retina, photoreceptors detect light and send electrical signals to retinal ganglion cells (RGCs), which then transmit the signal to the brain. GenSight’s optogenetic therapy skips the

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Fluorescent proteins light up science by making the invisible visible

Fluorescent proteins light up science by making the invisible visible
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