The San Francisco 49ers will take part in an international game in 2022. They will be the designated road team, traveling to face the "home team" Arizona Cardinals at Estadio Azteca in Mexico City on
SAN FRANCISCO (11-7) at GREEN BAY (13-4) Sunday, 8:15 p.m. EST, Fox OPENING LINE: Packers by 6, according to FanDuel Sportsbook. AGAINST THE SPREAD: 49ers 10-8; Packers 12-5. SERIES RECORD: Packers lead 38-32-1 LAST MEETING: Packers beat 49ers 30-28 on Sept. 26, in Santa Clara, California. LAST WEEK: 49ers won 23-17 at Dallas on Sunday; Packers had bye, lost to Lions 37-30.