Researchers introduce new tools for 3D research of cancer genome |
(KAIST)
A South Korean research team has built the world’s largest dataset and new browsing tools for the study of large-scale genomic rearrangements that could potentially cause cancer, the Korea Advanced Institute of Science and Technology said Monday.
Researchers led by KAIST professor Jung In-kyung and Korean Bioinformation Center professor Lee Byung-wook have collected and processed around 230 billion raw reads including 220 Hi-C samples. Based on the data, the team has completed construction of 400 different 3D architectures of human genomes.
Hi-C is a genome sequencing technique used to analyze the spatial genome organization of cells.