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Moderna : AACR INT Head & Neck Poster -April 08, 2024 at 04:52 pm EDT

AVEO Oncology Enrolls First Patient in Pivotal FIERCE-HN Clinical Trial to Evaluate Ficlatuzumab in Combination with ERBITUX® (cetuximab) in Patients with HPV-negative Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

Combination exhibits impressive activity in HPV-negative head and neck cancer

The combination of ficlatuzumab and cetuximab extended PFS for patients with pan-refractory recurrent or metastatic head and neck squamous cell carcinoma, according to randomized phase 2 study results.The benefit appeared confined to individuals with HPV-negative disease, and a phase 3 trial to further evaluate the regimen in that population is planned.

Unusual drug combo shows promise for advanced head, neck cancer without HPV

Unusual drug combo shows promise for advanced head, neck cancer without HPV
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