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New collaborative effort to produce anti-HIV monoclonal antibodies
The Hotung Molecular Immunology group at St George s, University of London has partnered with Leaf Expression Systems, a contract development and manufacturing organization, specializing in plant-based expression and production of proteins, to explore the feasibility of producing anti-HIV monoclonal antibodies at large scale.
Led by Professor Julian Ma, the research team is trying to address the challenge of producing monoclonal antibodies to treat HIV-positive women late in pregnancy, to reduce the risk of passing the virus to their babies. They have recently developed several candidate antibodies with broad activity against different HIV strains and potentially improved biological properties for administration to patients.