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Doctors Can Now Edit the Genes Inside Your Body

It sounds like science fiction, but dozens of people have undergone gene editing for cardiovascular disease and other conditions.

City ofUnited kingdomJulian gillmoreDouglas mannJames greenBetsy mckayJohn leonardSekar kathiresanKiran musunuruEverest base campUniversity of pennsylvaniaRegeneron pharmaceuticalsWashington university school of medicineUniversity college london centerNobel prize winningIntellia therapeutics

CRISPR gene therapy seems to cure dangerous inflammatory condition

Nine out of ten people in a trial of a CRISPR treatment for potentially life-threatening inflammatory reactions seem to have been cured

United kingdomUnited statesNew zealandPadmalal gurugama at cambridge university hospitalsJulian gillmore at university college londonHealth checkPadmalal gurugamaCambridge university hospitalsIntellia therapeuticsJulian gillmoreUniversity college londonGene therapy

Groundbreaking drug offers new hope for life-threatening heart condition

People diagnosed with a life-threatening cardiac condition have been given new hope, thanks to a ground-breaking new drug that protects the heart developed by researchers from UCL and the Royal Free Hospital.

United kingdomJulian gillmoreStephen neilRoyal navyUniversity college londonDivision of medicineNational amyloidosis centreRoyal freeNew england journalRoyal free hospitalHeart failure

BridgeBio Pharma Announces Publication of Positive Results from Phase 3 ATTRibute-CM Study of Acoramidis for Patients with Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in the New England Journal of Medicine

ATTRibute-CM demonstrated a significant treatment effect of acoramidis on the primary endpoint (a hierarchical analysis inclusive of all-cause mortality (ACM) and frequency of cardiovascular-related hospitalization (CVH)), with a Win Ratio of 1.8 (p

United statesUnited kingdomJonathan foxBio cardiorenalJulian gillmoreEuropean society of cardiology congressAmerican heart association scientific sessionsBridgebio pharma incUnited kingdom national amyloidosis centreUniversity college london centre for amyloidosisUs social security administrationBridgebio pharmaNew england journalProfessor julian gillmoreUniversity college londonUnited kingdom national amyloidosis

Across the board benefits seen with acoramidis for transthyretin amyloid cardiomyopathy

Across the board benefits seen with acoramidis for transthyretin amyloid cardiomyopathy
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Julian gillmoreByregina schafferRichard smithBio pharmaUk national amyloidosis centreUniversity college london centre for amyloidosisUniversity college london centreAmyloidosis centreBridgebio pharmaThenew england journalKansas city cardiomyopathy questionnaireOverall summary