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A large trial of low-dose amitriptyline resulted in nearly twice as many people reporting symptom relief for IBS as placebo, with researchers suggesting that GPs should be offer the drug more often.

United kingdomGlasgow cityJudith danbyHazel everittAlexander fordUnited kingdom national institute for healthCare researchUniversity of southamptonNational institute for healthUniversity of leedsRoyal collegeIrritable bowel syndromeSecond line treatmentGeneral practitionersAnnual conferenceUnited european gastroenterology