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Study uncovers a new paradigm for the role of the thymus in pregnancy How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – has now discovered that important changes in the thymus occur in order to prevent miscarriages and gestational diabetes. The results are published in the journal Nature. Female sex hormones instruct the thymus, a central organ of the immune system, to produce specialized cells called Tregs to deal with physiological changes to arise during pregnancy, the study revealed. The researchers also found that RANK, a receptor expressed in a part of the thymus called the epithelium, is the key molecule behind this mechanism. The study is an international research effort including scientists from IMBA, the University of British Columbia, the Karolinska Institutet and the Medical University of Vie

United kingdomBritish columbiaKarolinska institutetJosef penningerMagdalena paolinoAlexandra kautzky willerEmily hendersonUniversity of british columbiaLife sciences instituteUniversity of birminghamUniversity of viennaCemm instituteMolecular biotechnologyAustrian academyMedical universityஒன்றுபட்டது கிஂக்டம்