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Scientists Engineer Human T Cells 100x More Potent at Killing Cancer Cells

Scientists Engineer Human T Cells 100x More Potent at Killing Cancer Cells
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Students Share Reflections at Anatomy: Service of Gratitude

The Yale School of Medicine MD Class of 2026 held an Anatomy: Service of Gratitude on September 29. It was framed around musical, visual, and written art that

Smart Cell Therapies for Solid Cancers Ready to Move Towards Clinical Trials

MRI of glioblastomas. Immunotherapies that fight cancer have been a life-saving advancement for many patients, but the approach only works on a few types of malignancies, leaving few treatment options for most cancer patients with solid tumors. Now, in two related papers published April 28, 2021, in Science Translational Medicine, researchers at UCSF have demonstrated how to engineer smart immune cells that are effective against solid tumors, opening the door to treating a variety of cancers that have long been untouchable with immunotherapies. By “programming” basic computational abilities into immune cells that are designed to attack cancer, the researchers have overcome a number of major hurdles that have kept these strategies out of the clinic up to now. The two new papers show that the resulting “smart” therapies are more precise, flexible and thorough than previous approaches, and the researchers say that their approach may be ready for clinical trials in the near fut

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