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Research Refutes Early-Onset Complex Disease Theories

Research Refutes Early-Onset Complex Disease Theories
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United statesSoult ukpyolsiSouth koreaTonii pollinJosepm mercaderElvira isganaitisMoreyw haymondElizabetht jensenCatherine pihokerLorim laffelJennifer toddShylaja srinivasanJosec florezLynnel levitskyJason flannickAmyk mottl

Genetic Variants Associated With Response to Type 2 Diabetes Drugs Identified

Researchers have identified genetic variants associated with acute response to metformin and glipizide, medications used to treat type 2 diabetes.

United statesJosec florezJosephine liTechnology networkDiabetes prevention programEndocrine divisionMedicine at harvard medical schoolMassachusetts general hospitalMass general brighamDiabetes unitMedical schoolAcute responseHarvard medical

Genetic variation linked to treatment response to commonly prescribed type 2 diabetes medication

USA: The Massachusetts General Hospital (MGH) researchers have identified genetic variants associated with response to glucose-lowering medications: glipizide and metformin. The findings, described in.

United statesJosec florezJosephine liMedicine at harvard medical schoolDiabetes prevention programInstructor in medicine at harvard medical schoolEndocrine divisionMassachusetts general hospitalDiabetes unitHarvard medical schoolAcute responseHarvard medicalType 2 diabetesBlood sugar levels

Genetic Variants Impact Response to Type 2 Diabetes Treatment

Genetic Variants Impact Response to Type 2 Diabetes Treatment
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United statesKatherine figueroaJosec florezLauran brennerPhilip schroederVarinderpal kaurJosephine liAaron leongMiriams udlerAlicia huertaJosepm mercaderMedicine at harvard medical schoolJoslin clinical research centerDiabetes prevention programTranslational science centerHarvard medical school

Additive effects of genetic, socioeconomic factors account for the prevalence of type 2 diabetes and obesity

New research led by investigators at Massachusetts General Hospital, a founding member of Mass General Brigham, indicates that socioeconomic and genetic factors likely interact in an additive way to affect people's risks of developing obesity and type 2 diabetes.

United statesJosec florezJoanneb coleBrigham biobankAlisak manningEmily hendersonTimothyd majarianMiriam udlerSara cromerChiragm lakhaniMiriams udlerJordi merinoSherri annm burnett bowiePhilip schroederJosepm mercaderChiragj patel