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Study shows drug helps reprogram macrophage immune cells, suppress prostate and bladder tumor growth

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

Ada tam srinivasan yegnasubramanianLauraa senaKaraa lombardoJelani zarifKennethm aduseiRobertd leoneEdwardj pearceBarbara slusherMonali praharajElizabetha thompsonRaekwona williamsRoberte meyerhoffJohns hopkinsXiaoxu wangThomasr nirschlAlexj lee

Drug helps reprogram macrophage immune cells, suppress prostate and bladder tumor growth

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to new research.

United statesJohns hopkins universityRobertd leoneKennethm aduseiJonathan powellBarbara slusherXiaoxu wangLiang zhaoAda tam srinivasan yegnasubramanianAlexj leeDebebe theodrosKaraa lombardoThomasr nirschlEdwardj pearceMonali praharajJelani zarif

The accidental discovery to treat IBD

The accidental discovery to treat IBD
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Barbara slusherLou gehrigIvanhoe newswireJohns hopkins drug discoveryProfessor slusher

Medical Moment: The accidental discovery to treat inflammatory bowel disease

Medical Moment: The accidental discovery to treat inflammatory bowel disease
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Barbara slusherJohns hopkins drug discovery

New drug combination may improve treatment for rare nerve sheath tumors

Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies led by investigators at the Johns Hopkins Kimmel Cancer Center and Johns Hopkins Drug Discovery.

National institutes of healthUnited statesCzech republicJohns hopkins universityNorthwestern universityKathryn lembergBarbara slusherChristinea pratilasVerena staedtkeDianee petersNaziba nuhaJohns hopkinsLiang zhaoJoanna marieh aguilarYing wuMaryland innovation initiative award