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Adding methotrexate to pegloticase for gout increases response rate through 52 weeks

Adding methotrexate to pegloticase for gout increases response rate through 52 weeks
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United statesJohnk botsonOrthopedic physicians alaska

Horizon Therapeutics (HZNP) Announces Sustained Patient Response to KRYSTEXXA Injection with Methotrexate Compared to KRYSTEXXA Alone

Horizon Therapeutics (HZNP) Announces Sustained Patient Response to KRYSTEXXA Injection with Methotrexate Compared to KRYSTEXXA Alone
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United statesJohnk botsonAda kumarGout patients using dual energy computed tomographyEnergy computed tomographyAmerican college of rheumatology convergenceAlaska rheumatology allianceAmerican collegeRheumatology convergenceOrthopedic physiciansSafety studyIncrease response ratesReceiving pegloticaseMonosodium urate crystal deposit volume duringPatients treatedPegloticase plus methotrexate co therapy

Horizon Therapeutics plc: Sustained Patient Response to KRYSTEXXA (pegloticase) Injection with Methotrexate Compared to KRYSTEXXA Alone Shown through Month 12 in MIRROR Randomized Controlled Trial

Month 12 results from MIRROR randomized controlled trial to be featured on Nov. 13, 11:45 a.m. EST during plenary session at the American College of Rheumatology Convergence 2022 Imaging

United statesAmanda phranerClin rheumatolTina venturaJohnk botsonAda kumarRay gordonErin linnihanEnergy computed tomographyProduct communicationsPatients with uncontrolled gout coAmerican college of rheumatology convergenceExchange commissionGout patients using dual energy computed tomographyAlaska rheumatology allianceAmerican college

Horizon Therapeutics plc: Horizon to Highlight Novel Insights in Gout Care During the American College of Rheumatology Convergence 2022

Meeting plenary session to feature 12-Month data from MIRROR randomized controlled trial of KRYSTEXXA (pegloticase) injection with methotrexate - Horizon Therapeutics plc (Nasdaq: HZNP) today announced

United statesAmanda phranerTina venturaJohnk botsonRay gordonErin linnihanEnergy computed tomographyProduct communicationsAmerican college of rheumatology convergencePatient mental health outcomesGout patients using dual energy computed tomographyAlaska rheumatology allianceAmerican collegeRheumatology convergenceSafety studyIncrease response rates

Horizon Therapeutics plc: FDA Approves KRYSTEXXA (pegloticase) Injection Co-Administered With Methotrexate, Expanding the Labeling to Help More People with Uncontrolled Gout Achieve a Complete Response to Therapy

Approval based on MIRROR randomized controlled trial, which showed significant improvement and sustained patient response to KRYSTEXXA with methotrexate compared to KRYSTEXXA alone Trial

United statesAmanda phranerClin rheumatolTina venturaJohnk botsonRay gordonErin linnihanElizabethhz thompsonProduct communicationsPatients with uncontrolled gout coDrug administrationExchange commissionAlaska rheumatology allianceBiologics license applicationOrthopedic physiciansPrescribing information