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Study reveals mutations that drive therapy-related myeloid neoplasms in children

 E-Mail IMAGE: Xiaotu Ma, Ph.D., St. Jude Computational Biology, and Jeffery Klco, M.D., Ph.D., St. Jude Pathology view more  Credit: St. Jude Children s Research Hospital Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis. Scientists at St. Jude Children s Research Hospital have characterized the genomic abnormalities of 84 such myeloid neoplasms, with potential implications for early interventions to stop the disease. A paper detailing the work was published today in Nature Communications. The somatic (cancer) and germline (inherited) genomic alterations that drive therapy-related myeloid neoplasms in children have not been comprehensively described, until now. The researchers used a variety of sequencing techniques (whole exome, whole genome and RNA) to characterize the genomic profile of 84 pediatric therapy-related myeloid neoplasms. The data came from

St Jude researchers develop tool to paint cancer genome and reveal tumor secrets

Xin Zhou, Ph.D., and Jinghui Zhang, Ph.D., chair, both of St. Jude Computational Biology, helped develop a tool to provide researchers the ability to.

CNN Around the World June 26, 2013 16:38:00

erroneous. it can t define marriage for itself. john, i m just curious and it goes to how the decisions were outlined today too. the question being how are you harmed by this decision? how is anyone harmed by this decision? one has to look at how society had benefitted from traditional marriage to answer that. when you destroy or redefine the institution, all of society will be harmed. society that s put such stock in the institution as a counter balance to government and the way we raise our children. how is that harmed? you make it something about adults and making children irrelevant. does it concern you at all that the public opinion seems to be in a different place where you are. the latest cnn poll showing back in 2008 you had 44% in support of same-sex marriage.

CNN Around the World June 26, 2013 16:37:00

same-sex couples from the same benefits that straight couples get. the court weighing in on california s proposition 8. the justices said prop 8 supporters have no legal standing to defend the law. that ruling clears the way for same-sex marmgs to resume in california. joining us from the steps of supreme court is john easton. clearly this was not a winning day for you or your team. what do you make of the decisions from the supreme court? where do you go next? we think the court got it wrong in both decisions. section 2 remains in place. justice kennedy recognizes that the state s define marriage policy for their states. oddly that decision in doma suggests the trial court ruling in the proposition 8 case which is still on the books is

WHUT White House Chronicles July 26, 2009

captioned by the national captioning institute www.ncicap.org hello, i m llewellyn king, host of white house chronicle, which is coming right up, but first, a few thoughts of my own. >as you know, the country has been roiled by the debate over energy in the age of obama. we are here in san francisco where the edison electric institute is holding a meeting with the purpose of finding out more about the future of electricity. what is it going to cost us? how will we generate it? it is a terribly a vital service that we all depend on. you know, sentences go is a city that does different things to different people. i think this is the home of i think of this as the home of william randolph hearst and his newspapers that would not have been if he or his newspapers had not come on the scene at the same time as electricity, to turn his presses, to make type out of lead. i think first of electricity and of this really great american city, sentences go. i hope we can tell our

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