Researchers from Massachusetts General Hospital and Brigham and Women’s Hospital have reprogrammed the tumor microenvironment of liver cancer using mRNA nanoparticles.
Scientists and researchers never fail to amaze us with their dedication to making breakthrough discoveries that can save life even from life-threatening diseases
Get latest articles and stories on Science at LatestLY. Scientists and researchers never fail to amaze us with their dedication to making breakthrough discoveries that can save life even from life-threatening diseases. In a recent study, a team of researchers from Massachusetts General Hospital (MGH) and Brigham and Women s Hospital (BWH) restored the function of gene that helped in cancer suppression. Science News | Researchers Restore Function in Gene That Suppresses Liver Cancer, Enhances Immunotherapy.
The p53 master regulator gene function can be restored using mRNA nanoparticles, and when combined with immune checkpoint blockade the nanoparticles significantly increased antitumor immune responses in hepatocellular carcinoma laboratory models.