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UK Begins First COVID-19 Human Challenge Trial What Can Participants Expect?

UK Begins First COVID-19 Human Challenge Trial. What Can Participants Expect? 10/04/2021 Image: Ivan Diaz/Unsplash Jimmy Bernot watched with interest as the nurse carefully transferred a small amount of liquid containing dozens of hookworm larvae onto a piece of gauze, and then placed it on his wrist. Bernot couldn’t see the larvae – at just about half a millimetre long, they are all but invisible – but he could soon feel them: a tingling, itchy sensation as the worm larvae wriggled through his skin and into his bloodstream. From there, Bernot knew, the hookworms would travel to his lungs. Eventually, they would make their way up from his lungs, slip down his oesophagus, pass through his stomach, attach themselves to the lining of his small intestine, and begin to suck his blood.

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