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COVID-19 Vaccines May Not Be Effective In 3% Of US Population: Here s Why
KEY POINTS
Immunosuppressive drugs, steroids affect the body s response to the vaccine
Health experts say immunocompromised Americans may need boosters regularly
COVID-19 vaccines may not work fully or at all in 3% of the population in the United States, new research showed. Early data suggests that the vaccines offer a weaker response in people who take immunosuppressive drugs and, potentially, steroids.
Immunocompromised Americans which make about 3% to 4% of the U.S. population may not be protected against the novel coronavirus despite being fully vaccinated. According to the research, 15% to 80% of people with underlying medical conditions, including specific blood cancers or previously organ transplants, are generating fewer antibodies, The Washington Post reported.
COVID-19 Vaccines May Not Be Effective In This Group Of Americans By Danielle Ong
on May 19 2021 12:21 PM Less than 60 percent of US adults have received at least one Covid vaccine injection, and authorities are scrambling to convince the rest to do so AFP / Angela Weiss
COVID-19 vaccines may not work fully or at all in 3% of the population in the United States, new research showed. Early data suggests that the vaccines offer a weaker response in people who take immunosuppressive drugs and, potentially, steroids.
Immunocompromised Americans which make about 3% to 4% of the U.S. population may not be protected against the novel coronavirus despite being fully vaccinated. According to the research, 15% to 80% of people with underlying medical conditions, including specific blood cancers or previously organ transplants, are generating fewer antibodies, The Washington Post reported.
May 5, 2021
Therapeutic drug monitoring, half-dosing may not be ready for prime-time
Therapeutic drug monitoring (TDM) for patients with immune-mediated inflammatory diseases did not lead to better clinical remission rates, while routine dose reduction of anti-rheumatic drugs for patients with rheumatoid arthritis (RA) in remission offered modest benefits, according to two Norwegian trials.
In the NOR-DRUM Part A trial, clinical remission at week 30 was achieved in 50.5% of 198 patients with TDM versus 53% of 200 patients in the standard therapy group, for an adjusted difference of 1.5% (95% CI −8.2% to 11.1%,
P=0.78), reported Silje Watterdal Syversen, MD, PhD, of Diakonhjemmet Hospital in Oslo, and co-authors.
In the ARCTIC REWIND trial, disease flare occurred in 25% of 77 patients in the half-dose conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) group versus 6% in the stable-dose csDMARD group for a risk difference of 18% (95% CI 7%-29%), reported Si
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