A Nature survey finds that scientists are concerned, as well as excited, by the increasing use of artificial-intelligence tools in research. A Nature survey finds that scientists are concerned, as well as excited, by the increasing use of artificial-intelligence tools in research.
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February 2, 2021, by NCI Staff
PDX mice largely retain the genetics of the human tumors from which they were initially created, a new study shows.
Credit: Adapted from image provided courtesy of Jackson Laboratory.
Mouse models are among the most valuable tools in cancer research. Researchers use them for many types of studies, from identifying possible new cancer treatments to finding new clues about cancer biology.
But mice aren’t humans. So developing mouse models that provide meaningful research results namely, by ensuring they replicate how cancer behaves in humans as closely as possible has been a high priority for the research community. Now, a large study from an international group of researchers has provided some strong reassurance that an increasingly relied-upon type of mouse model, known as PDX mice, does just that.