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Benchtop machine automates synthesis of drug screening hits

Benchtop machine automates synthesis of drug screening hits
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Harnessing organisation of cell surface

Automated organic synthesis made easier with capsule-based console

By Jack Washington2021-05-12T08:01:00+01:00 Chemists in Switzerland have developed a standardised console for the automated synthesis of complex organic molecules. 1 Using prepacked capsules, and requiring minimal involvement from the user, this instrument produces and purifies drug-like compounds at the push of a button. Automated organic synthesis machine Source: © Jeffrey Bode/ ETH Zurich The team behind this automated organic synthesis machine hope organic chemists will use their systemt o become developers who package their methods into integrated, user-friendly packages that can be used immediately in a safe and convenient fashion Automating chemical synthesis has been a long-standing goal in the scientific community, and with ever-increasing technological capabilities, the field has experienced vast progress in recent years. Traditionally, automated reaction systems perform simple, iterative reactions to make chain-like molecules such as peptides, DNA and oligomers. A

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