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Study examines artemisinin-based combination therapy as first-line treatment for malaria
When a mosquito begins to nibble on you, it is not merely feeding on your blood, it is also injecting its saliva into your skin. If that saliva happens to be full of parasites carrying malaria or other diseases from its last victim, then most likely you will become infected, too.
The first-line treatment for malaria, caused by the P. Falciparum parasite, is artemisinin-based combination therapy, which provides a one-two punch. The drug artemisinin (derived from the Asian Artemisia annua or sweet wormwood) is combined with a quinoline-based compound. Artemisinin weakens the parasite by oxidizing it; the quinoline drug kills it.