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Gamasutra - Best of 2020: The trends and events that defined the year for game devs

); } The sun is setting on 2020, a year dominated by political upheaval, a once-in-a-century global pandemic, and no small amount of other front-page news events that kept us all glued to our phones night after night. In the age of doomscrolling, the game industry churned on, buoyed by both unexpected success from the prevalence of lockdown orders across the globe and rocked by the same upheavals that impacted ordinary folks around the globe. Here s a breakdown of the 10 trends and events that defined our industry this year. Maybe someday we ll learn some lessons from them. The Fucking Pandemic For better and for worse the global spread of COVID-19 reshaped the video game industry in ways that will be felt for years to come. Large studios suddenly developed robust remote work infrastructure. Physical events that shaped the year s marketing cycle were canceled. Developers of all stripes saw their daily average users spike upward, and multiple companiesreported huge increases to

New screening platform can be used to discover more effective drugs for type 1 diabetes

New screening platform can be used to discover more effective drugs for type 1 diabetes With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving. In type 1 diabetes mellitus, the body s immune system attacks and destroys insulin-producing β-cells. As a result, people living with type 1 diabetes lose insulin secretion and encounter difficulty regulating glucose levels especially after meals. Drugs developed to proliferate β-cells often are inefficient and have off-target effects that can dysregulate other cell types and pancreatic hormone production. To address these issues, researchers at Brigham and Women s Hospital and the Broad Institute teamed up to design next-generation β-cell-targeting proliferators: zinc-binding prodrugs (ZnPD). To achieve this, the researchers engineered a new screening platform, the Disque Platform, to better represent β-cells in the lab. Utilizing the D

New screening platform leads to discovery of next-generation prodrugs for type 1 diabetes

 E-Mail With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving. In type 1 diabetes mellitus, the body s immune system attacks and destroys insulin-producing β-cells. As a result, people living with type 1 diabetes lose insulin secretion and encounter difficulty regulating glucose levels especially after meals. Drugs developed to proliferate β-cells often are inefficient and have off-target effects that can dysregulate other cell types and pancreatic hormone production. To address these issues, researchers at Brigham and Women s Hospital and the Broad Institute teamed up to design next-generation β-cell-targeting proliferators: zinc-binding prodrugs (ZnPD). To achieve this, the researchers engineered a new screening platform, the Disque Platform, to better represent β-cells in the lab. Utilizing the Disque Platform, researchers identified a ZnPD drug which exhibited a 2.4-fold in

Transcripts For CNBC Squawk Box 20120911

there are observances taking place in new york, washington, pennsylvania and many other parts of this country. we have aol chairman and ceo tim armstrong and kenny dichter teaming up to try to honest or the victims and help their families. both will be joining us to talk about their work with action america at 6:50 eastern time. first, though, let s bring you up to speed on this morning s top stories. and welcome back. nice to see you back and feeling better. let s talk about some of the headlines this morning. germany s high court will be ruling on the legality of the eurozone permanent bailout fund tomorrow. the court rejected a last meant plea to postpone. it s going to decide tomorrow whether to issue an injunction that would prevent the country s president from ratifying germany s participation in the european mechanism and fiscal pact. optimism they will back the bailout fund september tnt thee higher this morning. and the sale of aig to under 22%. but here s the impo

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