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Human pangenome reference will enable more complete and equitable understanding of genomic diversity

Human pangenome reference will enable more complete and equitable understanding of genomic diversity
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Human Pangenome Reference to Enhance Genomic Diversity Study

Human Pangenome Reference to Enhance Genomic Diversity Study
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Inclusive new tool makes genomic research better reflect world s diversity

Inclusive New Tool Makes Genomic Research Better Reflect World s Diversity

Inclusive New Tool Makes Genomic Research Better Reflect World s Diversity
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Pangenomic Mapping Tool Betters Structural Variant Identification

Data from short-read sequencing up to a few hundred base pairs in length are computationally mapped to source locations and identities in a reference genome. However, the use of a single linear reference sequence generates bias in interpreting genetic variations. Scientists have now developed a new algorithmic tool they call Giraffe that can quickly and accurately map individual short sequencing reads to a pangenome reference representative of thousands of human genomes.

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