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Zanidatamab exhibits promising efficacy in advanced HER2-positive biliary tract cancer

CHICAGO — Zanidatamab exhibited durable antitumor activity among patients with previously treated advanced HER2-amplified biliary tract cancer, according to results of the phase 2B HERIZON-BTC-01 study presented at ASCO Annual Meeting.More than half of patients who received zanidatamb (Jazz Pharmaceuticals/Zymeworks) monotherapy survived at least a year and median OS exceeded 15 months.

United statesBymark leiserMindy valcarcelUniversity of texas md anderson cancer centerJazz pharmaceuticals zymeworksJazz pharmaceuticalsShubham pantCancer center

Zanidatamab induces response in refractory HER2-positive biliary tract cancer

Zanidatamab induces response in refractory HER2-positive biliary tract cancer
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United statesMindy valcarcelBymark leiserJazz pharmaceuticals zymeworksUniversity of texas md anderson cancer centerShubham pantCancer center

Zanidatamab induces response in refractory HER2-positive biliary tract cancer

CHICAGO — Zanidatamab induced durable responses among patients with previously treated HER2-amplified biliary tract cancer, according to study results presented at ASCO Annual Meeting.The agent also exhibited a manageable safety profile, investigators who conducted the phase 2b HERIZON-BTC-01 study concluded.

United statesAstellas pharmaMindy valcarcelBymark leiserBoehringer ingelheimBristol myers squibbJazz pharmaceuticals zymeworksUniversity of texas md anderson cancer centerEli lilly coEli lillyMirati therapeuticsShubham pantCancer center