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We thank Marcos Fernández-Barriales and colleagues for their comments on the summary
of orthodontic approaches that we provided in our Personal View of Sept 23, 2022.1
Although we agree that there is no definitive evidence on specific craniofacial features
that predispose to obstructive sleep apnoea (OSA) in children, as highlighted in a
systematic review (which itself was limited by low sample sizes of a few uncontrolled
studies),2 this hypothesis cannot and should not be dismissed prematurely.
Operator: Hello and welcome to the Moleculin Biotech Fiscal Year 2022 Quarterly Update Conference Call and Webcast. A question-and-answer session will follow the formal presentation.