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Scientists have proposed a modelling framework which could predict how antibiotic resistance will evolve in response to different treatment combinations, according to a study published in eLife.
Microscopy image of
Enterococcus faecalis. Image credit: Janice Haney Carr, USCDCP (CC0)
The research could help doctors optimise the choice, timing, dose and sequence of antibiotics used to treat common infections, helping to halt the growing threat of antibiotic resistance to modern medicine.
“Drug combinations are a particularly promising approach for slowing resistance, but the evolutionary impacts of combination therapy remain difficult to predict, especially in a clinical setting,” explains first author Erida Gjini, Researcher at the Department of Mathematics, Instituto Superior Tecnico, University of Lisbon, Portugal. “Interactions between antibiotics can accelerate, reduce
Model can predict how drug interactions influence antibiotic resistance
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Michigan Sees Spike In Legionnaires Cases
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PigProgress
Ventilation does not spread MRSA outside pig houses
Danish researchers put ventilation to the test in an attempt to see if methicillin-resistant Staphylococcus aureus (MRSA) could also spread outside pig houses.
The airborne spread of livestock-associated MRSA (LA-MRSA) through pig house ventilation hardly appears to be a source of infection for people outside the pig houses. That was the conclusion of recent Danish research, conducted by scientists from the Statens Serum Institut, the Technical University of Denmark as well as Aarhus University. The study was published in the peer-reviewed magazine
Frontiers in Veterinary Science. MRSA bacteria when viewed through a microscope. - Photo: CDC/ Janice Haney Carr
Dangerous Opportunistic Bacteria Rendered Nearly Harmless; Switching off Mechanism Behind Virulence Weakens Pathogen [Study]
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